The following is a clinical case of a dermatological disease with systemic repercussions that should be taken into account in the Primary Care consultation. This is a 55-year-old woman with a medical history of high blood pressure and COPD. She had no allergies, smoked 10 cigarettes a day, and had been on regular treatment with enalapril for the past 6 years and inhaled formoterol for the past 2 years. Due to a worsening of her lung disease, the pulmonologist decided to reinforce her inhalation treatment by discontinuing formoterol and prescribing a combination of indacaterol and glycopyrronium inhaled capsules. She attended the Primary Care clinic because, on the second day of the new inhaler treatment, she developed painful, erythematous patches on her cheeks and neck, accompanied by a low-grade fever (Fig. 1). The patient denied using any new cosmetics, had not made any changes to her usual diet, and did report sun exposure, albeit with adequate protection. She had not experienced any catarrhal symptoms in the previous days.
